TTD | Drug: D0F9OP

Drug General Information
Drug ID	D0F9OP
Former ID	DNC013900
Drug Name	Aerophobin-1
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551359]
Structure		Download 2D MOL 3D MOL
Formula	C15H16Br2N4O4
Canonical SMILES	COC1=C(C(C2(CC(=NO2)C(=O)NCCC3=CN=CN3)C=C1Br)O)Br
InChI	1S/C15H16Br2N4O4/c1-24-12-9(16)4-15(13(22)11(12)17)5-10(21-25-15)14(23)19-3-2-8-6-18-7-20-8/h4,6-7,13,22H,2-3,5H2,1H3,(H,18,20)(H,19,23)
InChIKey	MDUQIEXQKMPARD-UHFFFAOYSA-N
PubChem Compound ID	14484008
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Inhibitor	[551359]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 551359	Verongamine, a novel bromotyrosine-derived histamine H3-antagonist from the marine sponge Verongula gigantea. J Nat Prod. 1994 Jan;57(1):175-7.
Ref 551359	Verongamine, a novel bromotyrosine-derived histamine H3-antagonist from the marine sponge Verongula gigantea. J Nat Prod. 1994 Jan;57(1):175-7.

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Drug Information