Drug Information

Drug General Information
Drug ID
D0F2GG
Former ID
DIB019853
Drug Name
fenclonine
Synonyms
4-chlorophenylalanine; para-chlorophenylalanine; PCPA
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540709]
Structure
Download
2D MOL
Formula
C9H10ClNO2
InChI
InChI=1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
InChIKey
NIGWMJHCCYYCSF-UHFFFAOYSA-N
PubChem Compound ID
4652
PubChem Substance ID
118220, 3135847, 5350275, 7949976, 8149839, 8152858, 11336048, 11361287, 11364082, 11366644, 11369206, 11372830, 11374663, 11377368, 11462259, 11485173, 11489295, 11491581, 11492678, 11495002, 15463183, 17404849, 24278081, 26612319, 26679506, 26747140, 29223741, 47206090, 47515371, 47810805, 47959811, 48259290, 49865929, 49865930, 50104655, 50104656, 50104657, 51073443, 53777392, 53796052, 57322376, 79893731, 85084784, 85172960, 85172967, 85230975, 85788937, 87565413, 88837609, 89449664
Target and Pathway
Target(s) L-Tryptophan hydroxylase 2 Target Info Inhibitor [543388]
Phenylalanine hydroxylase Target Info Inhibitor [543386]
Tryptophan 5-hydroxylase-1 Target Info Inhibitor [543387]
BioCyc Pathway Phenylalanine degradation/tyrosine biosynthesisPWY66-401:Superpathway of tryptophan utilization
Serotonin and melatonin biosynthesis
KEGG Pathway Phenylalanine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Biosynthesis of amino acidshsa00380:Tryptophan metabolism
Serotonergic synapse
PANTHER Pathway 5-Hydroxytryptamine biosynthesis
PathWhiz Pathway Phenylalanine and Tyrosine MetabolismPW000163:Tryptophan Metabolism
WikiPathways SIDS Susceptibility Pathways
Biogenic Amine Synthesis
Metabolism of amino acids and derivatives
Abnormal metabolism in phenylketonuriaWP706:SIDS Susceptibility Pathways
Tryptophan metabolism
References
Ref 540709(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5240).
Ref 543386(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1240).
Ref 543387(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1241).
Ref 543388(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1242).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.