Drug Information

Drug General Information
Drug ID
D0WI3W
Former ID
DNC000507
Drug Name
Cystamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535104]
Structure
Download
2D MOL

3D MOL
Formula
C4H14Cl2N2S2
Canonical SMILES
C(CSSCCN)N.Cl.Cl
InChI
1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1H
InChIKey
YUFRRMZSSPQMOS-UHFFFAOYSA-N
CAS Number
CAS 56-17-7
PubChem Compound ID
5941
PubChem Substance ID
3132634, 8150051, 8153687, 17404860, 24858097, 24892384, 24893096, 25622683, 26612532, 26679647, 26747479, 26747480, 29213990, 29224966, 47184466, 49747207, 49969269, 50106056, 53777403, 56367750, 56436830, 57323067, 76028044, 85085067, 87565933, 89363786, 92124738, 92303702, 103821957, 104225899, 104310680, 109658282, 117446559, 117446965, 124637209, 125677122, 126603253, 134972598, 135573166, 135683707, 136999297, 143394358, 144035295, 160799961, 162055861, 162173125, 162267981, 163024439, 163564251, 163781276
Target and Pathway
Target(s) Glutamate--cysteine ligase regulatorysubunit Target Info Inhibitor [535104]
KEGG Pathway Glutathione metabolism
Metabolic pathways
PathWhiz Pathway Glutamate Metabolism
Glutathione Metabolism
Cysteine Metabolism
WikiPathways Transcriptional activation by NRF2
NRF2 pathway
Nuclear Receptors Meta-Pathway
Metabolism of amino acids and derivatives
Trans-sulfuration and one carbon metabolism
Trans-sulfuration pathway
Phase II conjugation
Glutathione metabolism
References
Ref 535104The gamma-glutamylcysteine synthetase of Onchocerca volvulus. Mol Biochem Parasitol. 2000 Dec;111(2):243-51.
Ref 535104The gamma-glutamylcysteine synthetase of Onchocerca volvulus. Mol Biochem Parasitol. 2000 Dec;111(2):243-51.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.