TTD | Drug: D06DSX

Drug General Information
Drug ID	D06DSX
Former ID	DNC009506
Drug Name	ESCHOLTZINE
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528095]
Structure		Download 2D MOL 3D MOL
Formula	C19H17NO4
Canonical SMILES	CN1C2CC3=CC4=C(C=C3C1CC5=CC6=C(C=C25)OCO6)OCO4
InChI	1S/C19H17NO4/c1-20-14-2-10-4-16-18(23-8-21-16)6-12(10)15(20)3-11-5-17-19(7-13(11)14)24-9-22-17/h4-7,14-15H,2-3,8-9H2,1H3/t14-,15-/m0/s1
InChIKey	PGINMPJZCWDQNT-GJZGRUSLSA-N
PubChem Compound ID	12304178
Target and Pathway
Target(s)	5-hydroxytryptamine 1A receptor	Target Info	Inhibitor	[528095]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (i) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528095	J Nat Prod. 2006 Mar;69(3):432-5.Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro.
Ref 528095	J Nat Prod. 2006 Mar;69(3):432-5.Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information