Drug Information

Drug General Information
Drug ID
D0UO2Z
Former ID
DNC010834
Drug Name
4-(2-(4-Cyclohexylphenylamino)ethyl)-1H-imidazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530846]
Structure
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2D MOL

3D MOL
Formula
C17H23N3
Canonical SMILES
C1CCC(CC1)C2=CC=C(C=C2)NCCC3=CN=CN3
InChI
1S/C17H23N3/c1-2-4-14(5-3-1)15-6-8-16(9-7-15)19-11-10-17-12-18-13-20-17/h6-9,12-14,19H,1-5,10-11H2,(H,18,20)
InChIKey
GEYDSVZUDGXVCV-UHFFFAOYSA-N
PubChem Compound ID
46222047
Target and Pathway
Target(s) Histamine H3 receptor Target Info Inhibitor [530846]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 530846J Med Chem. 2010 May 13;53(9):3840-4.Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.
Ref 530846J Med Chem. 2010 May 13;53(9):3840-4.Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.

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