Drug Information
Drug General Information | |||||
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Drug ID |
D03MTM
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Former ID |
DIB020119
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Drug Name |
JTE-013
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Synonyms |
JTE 013; JTE013; pyrazolopyridine analog
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539933] | ||
Structure |
Download2D MOL |
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Formula |
C17H19Cl2N7O
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InChI |
InChI=1S/C17H19Cl2N7O/c1-8(2)11-7-14(22-16-15(11)9(3)25-26(16)4)23-24-17(27)20-10-5-12(18)21-13(19)6-10/h5-8H,1-4H3,(H,22,23)(H2,20,21,24,27)
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InChIKey |
RNSLRQNDXRSASX-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | P2RY10 | Target Info | Antagonist | [529462] | |
Sphingosine-1-phosphate receptor-2 | Target Info | Antagonist | [526465] | ||
References | |||||
Ref 526465 | Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist. Biochem Biophys Res Commun. 2002 Dec 6;299(3):483-7. | ||||
Ref 529462 | Identification of the orphan GPCR, P2Y(10) receptor as the sphingosine-1-phosphate and lysophosphatidic acid receptor. Biochem Biophys Res Commun. 2008 Jul 11;371(4):707-12. |
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