Drug Information

Drug General Information
Drug ID
D07UFO
Former ID
DIB018530
Drug Name
20-HETE
Synonyms
20-hydroxyeicosatetraenoic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540701]
Structure
Download
2D MOL
Formula
C20H32O3
InChI
InChI=1S/C20H32O3/c21-19-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(22)23/h1,3-4,6-7,9-10,12,21H,2,5,8,11,13-19H2,(H,22,23)/b3-1-,6-4-,9-7-,12-10-
InChIKey
NNDIXBJHNLFJJP-DTLRTWKJSA-N
PubChem Compound ID
5283157
PubChem Substance ID
4266115, 11038791, 14718392, 14801405, 17395746, 24895546, 39316571, 49964844, 53790793, 57358870, 74666386, 113859256, 126524524, 126525564, 135079354, 137017133, 141469038, 162228697, 164796070, 178100926, 179293501, 184586025, 186022450, 210275257, 210280898, 226819771, 241138961, 250132926, 252371236, 252464960
Target and Pathway
Target(s) Short transient receptor potential channel 6 Target Info Activator [543855]
PANTHER Pathway Alzheimer disease-presenilin pathway
Pathway Interaction Database Endothelins
Nephrin/Neph1 signaling in the kidney podocyte
EPO signaling pathway
PAR1-mediated thrombin signaling events
Reactome Effects of PIP2 hydrolysis
TRP channels
Role of second messengers in netrin-1 signaling
WikiPathways Primary Focal Segmental Glomerulosclerosis FSGS
Platelet homeostasis
Netrin-1 signaling
GPCR downstream signaling
Effects of PIP2 hydrolysis
References
Ref 540701(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4103).
Ref 543855(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 491).

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