Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07TSW
|
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| Former ID |
DNC011282
|
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| Drug Name |
SALACINOL
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Phase 1/2 | [521814] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C9H18O9S2
|
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| Canonical SMILES |
C1C(C(C([S+]1CC(C(CO)OS(=O)(=O)[O-])O)CO)O)O
|
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| InChI |
1S/C9H18O9S2/c10-1-7(18-20(15,16)17)5(12)3-19-4-6(13)9(14)8(19)2-11/h5-14H,1-4H2/t5-,6-,7+,8-,9+,19?/m1/s1
|
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| InChIKey |
SOWRVDSZMRPKRG-XESHOGEWSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Maltase-glucoamylase, intestinal | Target Info | Inhibitor | [531230] | |
| Lysosomal alpha-glucosidase | Target Info | Inhibitor | [529528] | ||
| Pathway Interaction Database | Notch-mediated HES/HEY network | ||||
| PathWhiz Pathway | Starch and Sucrose MetabolismPW000159:Galactose Metabolism | ||||
| WikiPathways | Metabolism of carbohydrates | ||||
| References | |||||
| Ref 529528 | J Nat Prod. 2008 Jun;71(6):981-4. Epub 2008 Jun 12.Alpha-glucosidase inhibitor from Kothala-himbutu (Salacia reticulata WIGHT). | ||||
| Ref 531230 | Bioorg Med Chem. 2010 Nov 15;18(22):7794-8. Epub 2010 Sep 29.Probing the active-site requirements of human intestinal N-terminal maltase-glucoamylase: Synthesis and enzyme inhibitory activities of asix-membered ring nitrogen analogue of kotalanol and its de-O-sulfonated derivative. | ||||
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