Drug Information

Drug General Information
Drug ID
D0NY6U
Former ID
DIB019388
Drug Name
compound 26
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532721]
Structure
Download
2D MOL
Formula
C13H9FN4
InChI
InChI=1S/C13H9FN4/c14-9-3-1-2-8(6-9)10-4-5-11-12(18-10)13(15)17-7-16-11/h1-7H,(H2,15,16,17)
InChIKey
TWTLUQDFSDYZKO-UHFFFAOYSA-N
PubChem Compound ID
86703914
PubChem Substance ID
103924087, 224716963, 240525258, 242635812, 249565814
Target and Pathway
Target(s) MAP4K4 Target Info Inhibitor [532721]
NetPath Pathway FSH Signaling Pathway
TCR Signaling Pathway
PANTHER Pathway Apoptosis signaling pathway
Pathway Interaction Database EPHB forward signaling
TNF receptor signaling pathway
Ceramide signaling pathway
Direct p53 effectors
Reactome Oxidative Stress Induced Senescence
WikiPathways Insulin Signaling
MAPK Signaling Pathway
References
Ref 532721Discovery of selective 4-Amino-pyridopyrimidine inhibitors of MAP4K4 using fragment-based lead identification and optimization. J Med Chem. 2014 Apr 24;57(8):3484-93.
Ref 532721Discovery of selective 4-Amino-pyridopyrimidine inhibitors of MAP4K4 using fragment-based lead identification and optimization. J Med Chem. 2014 Apr 24;57(8):3484-93.

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