Drug Information

Drug General Information
Drug ID
D06VWH
Former ID
DNC000853
Drug Name
L-689,037
Drug Type
Small molecular drug
Indication Discovery agent Investigative [536008]
Structure
Download
2D MOL

3D MOL
Formula
C36H37ClN2O4
Canonical SMILES
CC(C)(C)CC(=O)C1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C<br />3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)O
InChI
1S/C36H37ClN2O4/c1-35(2,3)20-32(40)33-28-18-27(43-22-26-15-12-24-8-6-7-9-29(24)38-26)16-17-30(28)39(21-23-10-13-25(37)14-11-23)31(33)19-36(4,5)34(41)42/h6-18H,19-22H2,1-5H3,(H,41,42)
InChIKey
IUHIISLXVJPCRU-UHFFFAOYSA-N
CAS Number
CAS 136668-50-3
PubChem Compound ID
11758240
PubChem Substance ID
16866032, 23839434, 42800261, 80109439, 103290040, 128221484, 134339074, 135271405, 137828603, 141541207, 162389746, 163305867, 225146507, 228247166
Target and Pathway
Target(s) Arachidonate 5-lipoxygenaseactivating protein Target Info Inhibitor [536008]
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Leptin Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
WikiPathways Nuclear Receptors Meta-Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 5360085-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors. Mol Pharmacol. 1992 Feb;41(2):267-72.
Ref 5360085-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors. Mol Pharmacol. 1992 Feb;41(2):267-72.

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