Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0S4CE
|
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| Former ID |
DNC014788
|
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| Drug Name |
VL-0494
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C38H25N3O3
|
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CC=C(C=C2)C=CC3=C4C=CC(=O)C(=C4N5C6=CC=<br />CC=C6NC5=C3)CN7C(=O)C8=CC=CC=C8C7=O
|
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| InChI |
1S/C38H25N3O3/c42-34-21-20-28-27(19-16-24-14-17-26(18-15-24)25-8-2-1-3-9-25)22-35-39-32-12-6-7-13-33(32)41(35)36(28)31(34)23-40-37(43)29-10-4-5-11-30(29)38(40)44/h1-22,39H,23H2/b19-16+
|
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| InChIKey |
DVNWIOVXJYWOGK-KNTRCKAVSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cholecystokinin receptor type A | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Insulin secretion | |||||
| Pancreatic secretion | |||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2007 May 15;17(10):2749-55. Epub 2007 Mar 3.Synthesis and evaluation of novel benzimidazole derivative [Bz-Im] and its radio/biological studies. | ||||
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