Drug General Information
Drug ID
D0E9JD
Former ID
DIB020787
Drug Name
quinoline 2
Drug Type
Small molecular drug
Indication Discovery agent Investigative [543215]
Structure
Download
2D MOL
Formula
C23H24F2N2O2
InChI
InChI=1S/C23H24F2N2O2/c1-23(2,3)29-22(28)27-14-17(19-12-18(24)8-9-20(19)25)11-15-10-16-6-4-5-7-21(16)26-13-15/h4-10,12-13,17H,11,14H2,1-3H3,(H,27,28)/t17-/m1/s1
InChIKey
IRFHMTUHTBSEBK-QGZVFWFLSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Insulin-degrading Enzyme Target Info Inhibitor [533271]
KEGG Pathway Alzheimer's disease
WikiPathways Alzheimers Disease
References
Ref 543215(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8599).
Ref 533271Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo. J Biol Chem. 2015 Aug 14;290(33):20044-59.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.