| Drug General Information |
| Drug ID |
D05HOS
|
| Former ID |
DNC002837
|
| Drug Name |
Hydroxyaminovaline
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C5H12N2O2
|
| Canonical SMILES |
CC(C)C(C(=O)NO)N
|
| InChI |
1S/C5H12N2O2/c1-3(2)4(6)5(8)7-9/h3-4,9H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
|
| InChIKey |
USSBBYRBOWZYSB-SCSAIBSYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
838552, 7888071, 26703454, 36887565, 46508565, 51762563, 104632470, 129415060, 132631049, 137185103, 160965872, 162692513, 228616832
|
| Target and Pathway |
| Target(s) |
Collagenase 3 |
Target Info |
Inhibitor |
[1]
|
|---|
| Stromelysin-1 |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
TNF signaling pathway
|
|
Transcriptional misregulation in cancer
|
|
Rheumatoid arthritis
|
|
NetPath Pathway
|
IL1 Signaling PathwayNetPath_13:IL1 Signaling Pathway
|
|
IL4 Signaling Pathway
|
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PANTHER Pathway
|
Alzheimer disease-presenilin pathway
|
|
Plasminogen activating cascadeP00050:Plasminogen activating cascade
|
|
CCKR signaling map ST
|
|
Pathway Interaction Database
|
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signalingajdiss_2pathway:Posttranslational regulation of adherens junction stability and dissassembly
|
|
p75(NTR)-mediated signaling
|
|
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
|
|
Reactome
|
Collagen degradation
|
|
Degradation of the extracellular matrix
|
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Activation of Matrix Metalloproteinases
|
|
Assembly of collagen fibrils and other multimeric structuresR-HSA-1442490:Collagen degradation
|
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Assembly of collagen fibrils and other multimeric structures
|
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EGFR Transactivation by Gastrin
|
|
WikiPathways
|
Endochondral Ossification
|
|
Activation of Matrix Metalloproteinases
|
|
Oncostatin M Signaling Pathway
|
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AGE/RAGE pathway
|
|
Matrix MetalloproteinasesWP2769:Activation of Matrix Metalloproteinases
|
|
Gastrin-CREB signalling pathway via PKC and MAPK
|
|
Matrix Metalloproteinases
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
