Drug General Information |
Drug ID |
D0I0ML
|
Former ID |
DNC007747
|
Drug Name |
2-(2'-methyl-biphenyl-3-yl)-ethylamine
|
Drug Type |
Small molecular drug
|
Indication |
Discovery agent
|
Investigative |
[1]
|
Structure |
|
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2D MOL
3D MOL
|
Formula |
C15H17N
|
Canonical SMILES |
CC1=CC=CC=C1C2=CC(=CC=C2)CCN
|
InChI |
1S/C15H17N/c1-12-5-2-3-8-15(12)14-7-4-6-13(11-14)9-10-16/h2-8,11H,9-10,16H2,1H3
|
InChIKey |
KQRAKUVQYREATE-UHFFFAOYSA-N
|
PubChem Compound ID |
|
Target and Pathway |
Target(s) |
5-hydroxytryptamine 1A receptor |
Target Info |
Inhibitor |
[1]
|
5-hydroxytryptamine 7 receptor |
Target Info |
Inhibitor |
[1]
|
KEGG Pathway
|
cAMP signaling pathway
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Neuroactive ligand-receptor interaction
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Serotonergic synapsehsa04014:Ras signaling pathway
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Calcium signaling pathway
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Serotonergic synapse
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PANTHER Pathway
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Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
5HT1 type receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
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PathWhiz Pathway
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Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
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Reactome
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Serotonin receptors
|
G alpha (i) signalling eventsR-HSA-390666:Serotonin receptors
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G alpha (s) signalling events
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WikiPathways
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Serotonin HTR1 Group and FOS Pathway
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SIDS Susceptibility Pathways
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Monoamine GPCRs
|
GPCRs, Class A Rhodopsin-like
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GPCR ligand binding
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GPCR downstream signalingWP734:Serotonin Receptor 4/6/7 and NR3C Signaling
|
GPCR downstream signaling
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GPCRs, Other
|
References |
REF 1 | Bioorg Med Chem Lett. 2007 Jun 1;17(11):3018-22. Epub 2007 Mar 23.Novel aminoethylbiphenyls as 5-HT7 receptor ligands. |