Drug General Information
Drug ID	D0E5XM
Former ID	DIB020044
Drug Name	imbutamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538763]
Structure		Download 2D MOL
Formula	C7H13N3
InChI	InChI=1S/C7H13N3/c8-4-2-1-3-7-5-9-6-10-7/h5-6H,1-4,8H2,(H,9,10)
InChIKey	VJSUMPPMFYQOMP-UHFFFAOYSA-N
PubChem Compound ID	13499360
PubChem Substance ID	36744360, 49846721, 54020576, 103302059, 125757787, 129485055, 132593487, 135650379, 140071320, 163161033, 224776256, 229862279, 249782272
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Agonist	[526894]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538763	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1249).
Ref 526894	Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists. J Med Chem. 2003 Dec 4;46(25):5445-57.

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