Drug Information
Drug General Information | |||||
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Drug ID |
D0S6NE
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Former ID |
DIB020349
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Drug Name |
MF266-1
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [541316] | ||
Structure |
Download2D MOL |
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Formula |
C24H17ClF3NO3S
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InChI |
InChI=1S/C24H17ClF3NO3S/c25-18-6-7-21(32-14-15-4-2-1-3-5-15)20(11-18)19-8-9-33-22(19)16-10-17(13-29-12-16)23(30,31)24(26,27)28/h1-13,30-31H,14H2
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InChIKey |
JCCQFQOPADDTRS-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Prostaglandin E2 receptor, EP1 subtype | Target Info | Antagonist | [529322] | |
PANTHER Pathway | PI3 kinase pathway | ||||
References | |||||
Ref 529322 | MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis. J Pharmacol Exp Ther. 2008 May;325(2):425-34. |
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