Drug General Information
Drug ID	D00RCI
Former ID	DNAP001275
Drug Name	Teduglutide
Synonyms	Gattex (TN)
Drug Type	Small molecular drug
Indication	Short bowel syndrome [ICD9: 579.3; ICD10:K91.8]		Approved	[524696], [542060], [551871]
Company	NPS
Structure		Download 2D MOL 3D MOL
Formula	C164H252N44O55S
CAS Number	CAS 197922-42-2
PubChem Compound ID	16139605
PubChem Substance ID	15146221, 28734884, 40672959, 85197627, 135252598, 135260926, 160962974
ChEBI ID	ChEBI:72305
SuperDrug ATC ID	A16AX08
Target and Pathway
Target(s)	Glucagon-like peptide 2 receptor	Target Info	Modulator	[551871]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	G alpha (s) signalling events
	Glucagon-type ligand receptors
WikiPathways	GPCRs, Class B Secretin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 524696	ClinicalTrials.gov (NCT02099084) Short Bowel Syndrome and Teduglutide VS Placebo. U.S. National Institutes of Health.
Ref 542060	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7049).
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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