Drug Information
Drug General Information | |||||
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Drug ID |
D0C0SK
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Former ID |
DAP000633
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Drug Name |
Pyrimethamine
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Synonyms |
Chloridin; Chloridine; Chloridyn; Darachlor; Daraclor; Darapram; Daraprim; Daraprime; Daraprin; Diaminopyritamin; Erbaprelina; Ethylpyrimidine; Khloridin; Malacid; Malocid; Malocide; Maloprim; Pirimecidan; Pirimetamin; Pirimetamina; Primethamine; Pyremethamine; Pyrimethamin; Pyrimethaminum; Tindurin; Tindurine; Tinduring; Aventis Brand of Pyrimethamine; Glaxo Wellcome Brand of Pyrimethamine; GlaxoSmithKline Brand of Pyrimethamine; M alocid; Pirimetamina [Spanish]; Pyrimethamine Hcl; Wellcome Brand of Pyrimethamine;BW 5063; CP6; RP 4753; WR 2978; AZT + Pyrimethamine combination; BW 50-63; Daraprim (TN); EXR-101; Lactoferrin B & Pyrimethamine; Lactoferrin H & Pyrimethamine; Pirimetamina [INN-Spanish]; Pyrimethamine (Pyr); Pyrimethaminum [INN-Latin]; TCMDC-123831; TCMDC-125860; CRL-8131 & Pyrimethamine; CRL-8142 & Pyrimethamine; Fansidar (Pyrimethamine/Sulfadoxine); Pyrimethamine (JAN/USP/INN); Pyrimethamine [USAN:INN:BAN:JAN]; 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine; 2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine; 2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine; 5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine; 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE; 5-(4-CHLOROPHENYL)-6-ETHYL-2,4-PYRIMIDINEDIAMINE; 5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine; 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidi nediamine; 5-(4-chlorophenyl)-2,4-diamino-6-ethylpyrimidine; 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine; 5-(p-chlorophenyl)-6-ethyl-2,4-diaminopyrimidine; 5-[4-Chlorophenyl]-6-ethyl-2,4-pyrimidinediamine
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antimalarials
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Structure |
Download2D MOL |
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Formula |
C12H13ClN4
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InChI |
InChI=1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
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InChIKey |
WKSAUQYGYAYLPV-UHFFFAOYSA-N
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CAS Number |
CAS 58-14-0
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PubChem Compound ID | |||||
PubChem Substance ID |
9595, 69611, 602526, 640729, 640732, 642442, 642444, 823186, 855854, 7437605, 7847554, 7886730, 7980441, 8027594, 8027596, 8149512, 8153075, 10321489, 10528164, 11112140, 11335827, 11361066, 11363800, 11366362, 11368924, 11372601, 11374146, 11377086, 11406997, 11455757, 11462038, 11466065, 11467185, 11484408, 11485790, 11488702, 11491516, 11492309, 11494720, 15221150, 17389746, 22395175, 24870381, 26611904, 26679783, 26747011, 26747012, 26751532, 29224066, 46505987
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SuperDrug ATC ID |
P01BD01
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SuperDrug CAS ID |
cas=000058140
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Target and Pathway | |||||
Target(s) | Folate receptor alpha | Target Info | Modulator | [556264] | |
KEGG Pathway | Endocytosis | ||||
WikiPathways | Folate Metabolism | ||||
References | |||||
Ref 468031 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4800). | ||||
Ref 536773 | How many modes of action should an antibiotic have? Curr Opin Pharmacol. 2008 Oct;8(5):564-73. Epub 2008 Jul 30. |
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