TTD | Drug: D0F8HS

Drug General Information
Drug ID	D0F8HS
Former ID	DIB020540
Drug Name	NLX-101
Synonyms	F-15599; F 15599; F-15,599; F15599
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540546]
Structure		Download 2D MOL
Formula	C19H21ClF2N4O
InChI	InChI=1S/C19H21ClF2N4O/c1-13-9-24-17(25-10-13)11-23-12-19(22)4-6-26(7-5-19)18(27)14-2-3-16(21)15(20)8-14/h2-3,8-10,23H,4-7,11-12H2,1H3
InChIKey	WAAXKNFGOFTGLP-UHFFFAOYSA-N
PubChem Compound ID	11741361
PubChem Substance ID	16847876, 23825937, 42783416, 75035800, 103527155, 137129330, 137617033, 162221699, 172650223, 178100753, 198942007, 227596897, 248661505
Target and Pathway
Target(s)	5-hydroxytryptamine 1A receptor	Target Info	Modulator
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (i) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 540546	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3924).

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Drug Information