Drug Information
Drug General Information | |||||
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Drug ID |
D0V3FF
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Former ID |
DNC013170
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Drug Name |
D[Leu4,Orn8]VP
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Indication | Discovery agent | Investigative | [528674] | ||
Structure |
Download2D MOL |
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Formula |
C46H65N11O11S2
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Canonical SMILES |
CC(C)CC1C(=O)NC(C(=O)NC(CSSCCC(=O)NC(C(=O)NC(C(=O)N1)CC<br />2=CC=CC=C2)CC3=CC=C(C=C3)O)C(=O)N4CCCC4C(=O)NC(CCCN)C(=<br />O)NCC(=O)N)CC(=O)N
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InChI |
1S/C46H65N11O11S2/c1-26(2)20-31-41(63)55-34(23-37(48)59)44(66)56-35(46(68)57-18-7-11-36(57)45(67)52-30(10-6-17-47)40(62)50-24-38(49)60)25-70-69-19-16-39(61)51-32(22-28-12-14-29(58)15-13-28)42(64)54-33(43(65)53-31)21-27-8-4-3-5-9-27/h3-5,8-9,12-15,26,30-36,58H,6-7,10-11,16-25,47H2,1-2H3,(H2,48,59)(H2,49,60)(H,50,62)(H,51,61)(H,52,67)(H,53,65)(H,54,64)(H,55,63)(H,56,66)/t30-,31-,32-,33-,34-,35-,36-/m0/s1
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InChIKey |
FVVIZMMVAAKOOP-QJCLFNHPSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Oxytocin receptor | Target Info | Inhibitor | [528674] | |
Vasopressin V1b receptor | Target Info | Inhibitor | [528674] | ||
Vasopressin V1a receptor | Target Info | Inhibitor | [528674] | ||
Vasopressin V2 receptor | Target Info | Inhibitor | [528674] | ||
KEGG Pathway | Calcium signaling pathway | ||||
cAMP signaling pathway | |||||
Neuroactive ligand-receptor interaction | |||||
Oxytocin signaling pathwayhsa04020:Calcium signaling pathway | |||||
Vascular smooth muscle contractionhsa04020:Calcium signaling pathway | |||||
Vascular smooth muscle contractionhsa04080:Neuroactive ligand-receptor interaction | |||||
Vasopressin-regulated water reabsorption | |||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
PANTHER Pathway | Oxytocin receptor mediated signaling pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
PathWhiz Pathway | Vasopressin Regulation of Water Homeostasis | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
Myometrial Relaxation and Contraction Pathways | |||||
Oxytocin signaling | |||||
Gastrin-CREB signalling pathway via PKC and MAPK | |||||
Peptide GPCRs | |||||
GPCR ligand binding | |||||
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like | |||||
Regulation of Water Balance by Renal Aquaporins | |||||
GPCR downstream signaling | |||||
References |
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