Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03FZA
|
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| Former ID |
DNC012073
|
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| Drug Name |
FUSIDIENOL
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Terminated | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H12O7
|
||||
| Canonical SMILES |
COC(=O)C1=CC(=COC2=C1C(=O)C3=C(O2)C=CC=C3O)CO
|
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| InChI |
1S/C16H12O7/c1-21-15(20)9-5-8(6-17)7-22-16-12(9)14(19)13-10(18)3-2-4-11(13)23-16/h2-5,7,17-18H,6H2,1H3
|
||||
| InChIKey |
LJNGMSGIOXTZLN-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Protein farnesyltransferase beta subunit | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Terpenoid backbone biosynthesis | ||||
| Biosynthesis of antibiotics | |||||
| NetPath Pathway | TSH Signaling Pathway | ||||
| Reactome | Inactivation, recovery and regulation of the phototransduction cascade | ||||
| WikiPathways | Visual phototransduction | ||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004994) | ||||
| REF 2 | J Med Chem. 2002 Mar 28;45(7):1460-5.Modeling of binding modes and inhibition mechanism of some natural ligands of farnesyl transferase using molecular docking. | ||||
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