Drug Information

Drug General Information
Drug ID
D0D5BI
Former ID
DIB018636
Drug Name
5,6-epoxyeicosatrienoic acid
Synonyms
(+/-)5,6-EpETrE; (+/-)5,6-epoxy-8Z,11Z,14Z-eicosatrienoic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541454]
Structure
Download
2D MOL
Formula
C20H32O3
InChI
InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-19(23-18)16-14-17-20(21)22/h6-7,9-10,12-13,18-19H,2-5,8,11,14-17H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-
InChIKey
VBQNSZQZRAGRIX-QNEBEIHSSA-N
PubChem Compound ID
5283202
PubChem Substance ID
4266143, 11038817, 17395766, 17428107, 26754776, 26754777, 39316613, 48034838, 48110199, 50110773, 75307674, 92309863, 99300777, 99302295, 104046413, 113859382, 126524420, 135610103, 138179895, 141552177, 178102923, 179205539, 228613784, 242488434, 250132995, 252455587
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily V member 4 Target Info Activator [526681]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 541454(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6304).
Ref 526681Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature. 2003 Jul 24;424(6947):434-8.

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