TTD | Drug: D0N3YN

Drug General Information
Drug ID	D0N3YN
Former ID	DIB020607
Drug Name	ONO-3080573
Synonyms	ON3
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533273]
Structure		Download 2D MOL
Formula	C31H34O7
InChI	InChI=1S/C31H34O7/c1-19-26(35-2)16-22(17-27(19)36-3)29(32)28(38-25-14-20-6-4-5-7-21(20)15-25)18-37-24-10-8-23(9-11-24)31(12-13-31)30(33)34/h4-11,16-17,25,28-29,32H,12-15,18H2,1-3H3,(H,33,34)/t28-,29+/m0/s1
InChIKey	FVESDCZDESZGHA-URLMMPGGSA-N
PubChem Compound ID	91799238
PubChem Substance ID	251963609, 252166789
Target and Pathway
Target(s)	Lysophosphatidic acid receptor Edg-2	Target Info	Antagonist	[533273]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	PI3K-Akt signaling pathway
	Gap junction
	Pathways in cancer
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database	LPA receptor mediated events
Reactome	G alpha (q) signalling events
	G alpha (i) signalling events
	Lysosphingolipid and LPA receptors
WikiPathways	Myometrial Relaxation and Contraction Pathways
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 533273	Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 2015 Jun 18;161(7):1633-43.
Ref 533273	Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 2015 Jun 18;161(7):1633-43.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information