Drug Information
Drug General Information | |||||
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Drug ID |
D05CEU
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Former ID |
DAP000142
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Drug Name |
Flunarizine
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Synonyms |
Flufenal; Flunarizin; Flunarizina; Flunarizinum; Fluvert; Issium; Sibelium; Vertix; Zinasen; Apo-flunarizine capsules; Flunarizina [INN-Spanish]; Flunarizine (INN); Flunarizine [INN:BAN]; Flunarizinum [INN-Latin]; Novo-Flunarizine; R-14950; Sibelium (TN); (E)-1-(Bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)piperazine; (E)-1-[Bis-(p-fluorophenyl)methyl]-4-cinnamylpiperazine; 1-(Bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine; 1-[bis(4-fluorophenyl)methyl]-4-(3-phenylprop-2-en-1-yl)piperazine; 1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine
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Drug Type |
Small molecular drug
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Indication | Migraine [ICD9: 346; ICD10:G43] | Approved | [538455] | ||
Therapeutic Class |
Anticonvulsants
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Company |
Janssen Pharmaceutica
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Structure |
Download2D MOL |
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Formula |
C26H26F2N2
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Canonical SMILES |
C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)<br />F
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InChI |
1S/C26H26F2N2/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21/h1-15,26H,16-20H2/b7-4+
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InChIKey |
SMANXXCATUTDDT-QPJJXVBHSA-N
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CAS Number |
CAS 52468-60-7
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PubChem Compound ID | |||||
PubChem Substance ID |
7979238, 9208288, 10525243, 14879384, 26751607, 26751608, 44891609, 46507129, 47216516, 47216517, 47439976, 47515052, 47515053, 47515054, 47515055, 47588728, 47588729, 47736197, 48184716, 49698432, 50011452, 50104264, 50104265, 56365814, 57408889, 80028030, 81093273, 85787717, 85788409, 85788604, 90341204, 92308837, 92309757, 92711460, 96024666, 99300671, 99302189, 103050123, 103096316, 103153578, 103199419, 103928970, 104179181, 110096637, 117509719, 124526360, 124749784, 124883264, 124883265, 124883266
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SuperDrug ATC ID |
N07CA03
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SuperDrug CAS ID |
cas=052468607
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Target and Pathway | |||||
Target(s) | Voltage-dependent T-type calcium channel subunit alpha-1H | Target Info | Blocker | [535918], [537585] | |
PathWhiz Pathway | Muscle/Heart Contraction | ||||
Reactome | NCAM1 interactions | ||||
References |
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