Drug General Information
Drug ID	D0A4DR
Former ID	DNC000184
Drug Name	Alpha-methyl-alpha-phenylsuccinimide (MPS)
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[535283]
Structure		Download 2D MOL 3D MOL
Formula	C11H11NO2
Canonical SMILES	CC1(CC(=O)NC1=O)C2=CC=CC=C2
InChI	1S/C11H11NO2/c1-11(7-9(13)12-10(11)14)8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,12,13,14)
InChIKey	UDESUGJZUFALAM-UHFFFAOYSA-N
CAS Number	CAS 1497-17-2
PubChem Compound ID	92154
PubChem Substance ID	3139785, 5523075, 10225220, 10508657, 15487500, 24888515, 44423020, 50895990, 57335144, 57756349, 89376265, 103811202, 104406672, 114917450, 117600755, 118740850, 126428116, 129351640, 131544229, 135048809, 135367264, 142322690, 143904767, 162232356, 164763688, 170153068, 172912813, 176237859, 184571982, 184828065, 204408181, 223251956, 223972182, 227764513, 249991549, 252128891, 252261785, 252345033
Target and Pathway
Target(s)	Voltage-dependent T-type calcium channel alpha-1G subunit	Target Info	Blocker	[535283]
KEGG Pathway	MAPK signaling pathway
	Calcium signaling pathway
	Circadian entrainment
	Type II diabetes mellitus
PANTHER Pathway	Endogenous cannabinoid signaling
	GABA-B receptor II signaling
	Nicotine pharmacodynamics pathway
Pathway Interaction Database	Regulation of nuclear beta catenin signaling and target gene transcription
PathWhiz Pathway	Muscle/Heart Contraction
Reactome	NCAM1 interactions
WikiPathways	NCAM signaling for neurite out-growth
	Nicotine Activity on Chromaffin Cells
References
Ref 535283	Block of cloned human T-type calcium channels by succinimide antiepileptic drugs. Mol Pharmacol. 2001 Nov;60(5):1121-32.
Ref 535283	Block of cloned human T-type calcium channels by succinimide antiepileptic drugs. Mol Pharmacol. 2001 Nov;60(5):1121-32.

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