Drug Information

Drug General Information
Drug ID
D0L3XU
Former ID
DNC000018
Drug Name
(S)-UH-301
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541328]
Structure
Download
2D MOL

3D MOL
Formula
C16H24FNO
InChI
InChI=1S/C16H24FNO/c1-3-9-18(10-4-2)12-5-6-13-14(11-12)16(19)8-7-15(13)17/h7-8,12,19H,3-6,9-11H2,1-2H3/t12-/m0/s1
InChIKey
FNKBVTBXFLSTPB-LBPRGKRZSA-N
CAS Number
CAS 3416-24-8
PubChem Compound ID
122187
PubChem Substance ID
10239977, 11111940, 11111941, 14799115, 15221701, 24263028, 29302624, 47736728, 48110701, 48259478, 50064303, 50111273, 57340010, 74585724, 90340746, 103190155, 103925253, 104415246, 124750343, 134341199, 135077398, 135651091, 144239996, 179235766, 198976244, 231461172
ChEBI ID
ChEBI:47977
SuperDrug ATC ID
M01AX05
SuperDrug CAS ID
cas=003416248
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Antagonist [538050]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 541328(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 61).
Ref 538050Influence of 5-HT1A receptor antagonism on plus-maze behaviour in mice. II. WAY 100635, SDZ 216-525 and NAN-190. Pharmacol Biochem Behav. 1997 Oct;58(2):593-603.

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