Drug General Information
Drug ID
D00YZD
Former ID
DNCL002987
Drug Name
Dolutegravir
Synonyms
S/GSK1349572; DTG
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Approved [532651], [542387]
Company
GlaxoSmithKline
Structure
Download
2D MOL

3D MOL

Formula
C20H19F2N3O5
InChI
InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1
InChIKey
RHWKPHLQXYSBKR-BMIGLBTASA-N
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
J05AX12
Drug Resistance Mutation (DRM)
DRM DRM Info
Target and Pathway
Target(s) HIV integrase Target Info Modulator [532651]
References
Ref 5326512013 FDA drug approvals. Nat Rev Drug Discov. 2014 Feb;13(2):85-9.
Ref 542387(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7365).
Ref 5326512013 FDA drug approvals. Nat Rev Drug Discov. 2014 Feb;13(2):85-9.

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