Drug Information

Drug General Information
Drug ID
D05CPV
Former ID
DCL000783
Drug Name
Dronedarone
Synonyms
Multaq; Dronedarone [INN]; SR 33589; SR 33589B; Dronedarone (INN); Sanofi-Aventis brand of dronedarone; N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide; N-(2-Butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide; N-[2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl]methanesulfonamide; N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide
Drug Type
Small molecular drug
Indication Angina pectoris [ICD9: 413; ICD10:I20] Approved [542490], [551871]
Atrial fibrillation [ICD9: 272, 427.31; ICD10:E78, I48] Withdrawn from market [536095], [542490]
Company
Sanofi-Synthelabo
Structure
Download
2D MOL

3D MOL
Formula
C31H44N2O5S
InChI
InChI=1S/C31H44N2O5S/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3/h13-18,23,32H,5-12,19-22H2,1-4H3
InChIKey
ZQTNQVWKHCQYLQ-UHFFFAOYSA-N
CAS Number
CAS 141625-93-6
PubChem Compound ID
208898
PubChem Substance ID
9368719, 14861729, 17396708, 30413541, 49991104, 50605127, 53801270, 57399553, 85210065, 87350388, 92721602, 99246129, 103450658, 104040015, 109692880, 113442043, 123121569, 124899317, 125340836, 126619012, 126666952, 129941685, 131298725, 134339267, 134358403, 135184552, 137138586, 139991786, 144206559, 152258951, 160647796, 162011679, 162190611, 164825705, 165702342, 170465064, 174527431, 175268727, 175426865, 179322835, 184547228, 185974016, 187051768, 198991949, 223392235, 223659005, 224585881, 226483798, 251893827
SuperDrug ATC ID
C01BD07
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily A member 5 Target Info Blocker [536095]
PathWhiz Pathway Muscle/Heart Contraction
Reactome Voltage gated Potassium channels
WikiPathways Potassium Channels
References
Ref 536095New antiarrhythmic agents for atrial fibrillation and atrial flutter. Expert Opin Emerg Drugs. 2005 May;10(2):311-22.
Ref 542490(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7465).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536095New antiarrhythmic agents for atrial fibrillation and atrial flutter. Expert Opin Emerg Drugs. 2005 May;10(2):311-22.

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