Drug Information

Drug General Information
Drug ID
D08HDY
Former ID
DAP001174
Drug Name
Pivmecillinam
Synonyms
Coactabs; PMPC; Pivamdinocillin; Pivmecilinamo; Pivmecillinamum; Selexid; Amdinocillin Pivoxil; Amdinocillin pivoxil [USAN]; Mecillinam Pivaloyl Ester; Amdinocillin pivoxil (USAN); Amdinocillin, pivaloyloxymethyl ester; Coactabs (TN); Penomax (TN); Pivmecilinamo [INN-Spanish]; Pivmecillinam (INN); Pivmecillinamum [INN-Latin]; Ro 10-9071; Selexid (TN); [(2,2-dimethylpropanoyl)oxy]methyl 6beta-[(azepan-1-ylmethylidene)amino]-2,2-dimethylpenam-3alpha-carboxylate; [(2,2-dimethylpropanoyl)oxy]methyl (2S,5R,6R)-6-[(azepan-1-ylmethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; [(2,2-dimethylpropanoyl)oxy]methyl(2s,5r,6r)-6-{[(e)-azepan-1-ylmethylidene]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; Hydroxymethyl (2S,5R,6R)-6-(((hexahydro-1H-azepin-1-yl)methylene)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate pivalate (ester); 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 2,2-dimethylpropanoyloxymethyl (5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Drug Type
Small molecular drug
Indication Urinary tract infections [ICD9: 599; ICD10:N39.0] Approved [550761], [551871]
Therapeutic Class
Antibiotics
Structure
Download
2D MOL

3D MOL
Formula
C21H33N3O5S
Canonical SMILES
CC1(C(N2C(S1)C(C2=O)N=CN3CCCCCC3)C(=O)OCOC(=O)C(C)(C)C)<br />C
InChI
1S/C21H33N3O5S/c1-20(2,3)19(27)29-13-28-18(26)15-21(4,5)30-17-14(16(25)24(15)17)22-12-23-10-8-6-7-9-11-23/h12,14-15,17H,6-11,13H2,1-5H3/t14-,15+,17-/m1/s1
InChIKey
NPGNOVNWUSPMDP-HLLBOEOZSA-N
CAS Number
CAS 32886-97-8
PubChem Compound ID
115163
PubChem Substance ID
11112725, 11467081, 11468201, 11486669, 11540509, 17397046, 29296699, 32960712, 46506880, 47276875, 47425574, 47574671, 48170711, 49699390, 50124055, 50336055, 56464195, 57339026, 85788087, 103067976, 103084922, 104397736, 117583507, 124975251, 128734935, 134222311, 134999919, 137003758, 179339250, 180099904, 198990067, 226420454, 226420455, 241061837, 242323962, 242406744, 252345096, 252419870, 252480505
ChEBI ID
ChEBI:51210
SuperDrug ATC ID
J01CA08
SuperDrug CAS ID
cas=032886978
Target and Pathway
Target(s) DNA Target Info Binder [536997]
References
Ref 550761Drug information of Pivmecillinam, 2008. eduDrugs.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536997Association between antimicrobial consumption and resistance in Escherichia coli. Antimicrob Agents Chemother. 2009 Mar;53(3):912-7. Epub 2008 Dec 22.

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