Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D07BRZ
|
||||
Former ID |
DIB007857
|
||||
Drug Name |
LY-517717
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] | Phase 2 | [521582] | ||
Company |
Eli Lilly
|
||||
Structure |
Download2D MOL |
||||
Formula |
C27H33N5O2
|
||||
Canonical SMILES |
CN1CCC(CC1)N2CCN(CC2)C(=O)[C@H](NC(=O)c3ccc4cc[nH]c4c3)<br />c5ccccc5
|
||||
InChI |
1S/C27H33N5O2/c1-30-13-10-23(11-14-30)31-15-17-32(18-16-31)27(34)25(21-5-3-2-4-6-21)29-26(33)22-8-7-20-9-12-28-24(20)19-22/h2-9,12,19,23,25,28H,10-11,13-18H2,1H3,(H,29,33)/t25-/m1/s1
|
||||
InChIKey |
VYNKVNDKAOGAAQ-RUZDIDTESA-N
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Coagulation factor Xa | Target Info | Inhibitor | [531405], [531982] | |
KEGG Pathway | Complement and coagulation cascades | ||||
PANTHER Pathway | Blood coagulation | ||||
Pathway Interaction Database | Beta2 integrin cell surface interactions | ||||
PathWhiz Pathway | Coagulation | ||||
Reactome | Extrinsic Pathway of Fibrin Clot Formation | ||||
Intrinsic Pathway of Fibrin Clot Formation | |||||
Common Pathway of Fibrin Clot Formation | |||||
Gamma-carboxylation of protein precursors | |||||
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.