Drug Information

Drug General Information
Drug ID
D05UXF
Former ID
DCL000794
Drug Name
Emapunil
Drug Type
Small molecular drug
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Discontinued in Phase 2 [543259], [547175]
Company
Dainippon; Novartis
Structure
Download
2D MOL

3D MOL
Formula
C23H23N5O2
InChI
InChI=1S/C23H23N5O2/c1-3-27(15-17-10-6-4-7-11-17)20(29)16-28-22-19(26(2)23(28)30)14-24-21(25-22)18-12-8-5-9-13-18/h4-14H,3,15-16H2,1-2H3
InChIKey
NBMBIEOUVBHEBM-UHFFFAOYSA-N
CAS Number
CAS 226954-04-7
PubChem Compound ID
6433109
PubChem Substance ID
11620283, 14781360, 43026855, 50858459, 58108350, 103631320, 104114013, 114543024, 125745821, 126651473, 128678277, 134339277, 135253518, 162111795, 162818276, 179322855, 196409583, 198977567, 225100822, 230653838, 249582456, 249896050, 252158744, 252166904, 252450564, 252543643
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Agonist [536580]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 543259(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8704).
Ref 547175Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013611)
Ref 536580Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology. 2008 Aug;33(9):2080-92. Epub 2008 Jan 2.

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