Drug Information
Drug General Information | |||||
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Drug ID |
D06VCN
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Former ID |
DPR000133
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Drug Name |
Denagliptin
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Synonyms |
GW 823093; GW823093; (2S,4S)-1-[(2S)-2-amino-3,3-bis(4-fluorophenyl)propanoyl]-4-fluoro-pyrrolidine-2-carbonitrile
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Drug Type |
Small molecular drug
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Indication | Type 2 diabetes [ICD9: 250; ICD10:E11] | Phase 2/3 | [521900] | ||
Company |
Glaxo Smithkline
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Structure |
Download2D MOL |
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Formula |
C20H18F3N3O
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Canonical SMILES |
C1C(CN(C1C#N)C(=O)C(C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)N)F
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InChI |
1S/C20H18F3N3O/c21-14-5-1-12(2-6-14)18(13-3-7-15(22)8-4-13)19(25)20(27)26-11-16(23)9-17(26)10-24/h1-8,16-19H,9,11,25H2/t16-,17-,19-/m0/s1
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InChIKey |
URRAHSMDPCMOTH-LNLFQRSKSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Dipeptidyl peptidase IV | Target Info | Inhibitor | [537022] | |
KEGG Pathway | Protein digestion and absorption | ||||
NetPath Pathway | IL2 Signaling Pathway | ||||
TGF_beta_Receptor Signaling Pathway | |||||
References |
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