Drug Information
Drug General Information | |||||
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Drug ID |
D08SZO
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Former ID |
DIB001485
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Drug Name |
F-12458
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Synonyms |
CAAX tetrapeptide analogs, Pierre Fabre; F-12458; Farnesyl transferase inhibitors, Pierre Fabre; Ras inhibitor, Pierre Fabre
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Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Investigative | [1] | ||
Company |
Pierre Fabre SA
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Structure |
![]() |
Download2D MOL |
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Canonical SMILES |
c1(C(=O)N2CCN(c3ccc(N(C(=O)c4cc(Cl)ccc4)Cc4n(cnc4)Cc4cc<br />c(C#N)cc4)cc3)CC2)sc(cc1)Cl
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Target and Pathway | |||||
Target(s) | Protein farnesyltransferase beta subunit | Target Info | Inhibitor | [1] | |
KEGG Pathway | Terpenoid backbone biosynthesis | ||||
Biosynthesis of antibiotics | |||||
NetPath Pathway | TSH Signaling Pathway | ||||
Reactome | Inactivation, recovery and regulation of the phototransduction cascade | ||||
WikiPathways | Visual phototransduction | ||||
References | |||||
REF 1 | Recent progress in protein farnesyltransferase inhibition. IDrugs. 2000 Nov;3(11):1336-45. | ||||
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