Drug Information

Drug General Information
Drug ID
D0D8MD
Former ID
DNC001541
Drug Name
ZM-230487
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [545870]
Structure
Download
2D MOL

3D MOL
Formula
C24H26FNO4
Canonical SMILES
CCN1C2=C(C=CC1=O)C=C(C=C2)COC3=CC(=CC(=C3)C4(CCOCC4)OC)<br />F
InChI
1S/C24H26FNO4/c1-3-26-22-6-4-17(12-18(22)5-7-23(26)27)16-30-21-14-19(13-20(25)15-21)24(28-2)8-10-29-11-9-24/h4-7,12-15H,3,8-11,16H2,1-2H3
InChIKey
ZROVOGSXAWNIQB-UHFFFAOYSA-N
CAS Number
CAS 155944-23-3
PubChem Compound ID
132998
PubChem Substance ID
10243262, 14757688, 29311011, 57344339, 79973969, 99222710, 103601131, 104104311, 104378741, 125706120, 134340697, 134340700, 135087951, 137828708, 141541292, 162797211, 196377597, 231773290, 247455379
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [536489]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 545870Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005134)
Ref 536489Pharmacological nature of nicotine-induced contraction in the rat basilar artery: involvement of arachidonic acid metabolites. Eur J Pharmacol. 2007 Dec 22;577(1-3):109-14. Epub 2007 Aug 14.

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