Drug General Information
Drug ID
D00LBD
Former ID
DNC000930
Drug Name
Metazosin
Drug Type
Small molecular drug
Indication Cardiotonic [ICD10:I50] Discontinued in Phase 3 [545078]
Structure
Download
2D MOL

3D MOL

Formula
C18H25N5O4
Canonical SMILES
CC(C(=O)N1CCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC)OC
InChI
1S/C18H25N5O4/c1-11(25-2)17(24)22-5-7-23(8-6-22)18-20-13-10-15(27-4)14(26-3)9-12(13)16(19)21-18/h9-11H,5-8H2,1-4H3,(H2,19,20,21)
InChIKey
YEOTYALSMRNXLJ-UHFFFAOYSA-N
CAS Number
CAS 116728-65-5
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Alpha-1 adrenergic receptor Target Info Antagonist [537827]
References
Ref 545078Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002056)
Ref 537827Metazosin tablets (Kenosin) in the treatment of chronic congestive heart failure. Cas Lek Cesk. 1995 Sep 20;134(18):590-3.

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