Drug Information

Drug General Information
Drug ID
D00KJO
Former ID
DIB006241
Drug Name
MUT-056399
Synonyms
Fab-001; MUT-1; MUT-2; MUT-3; MUT-37307; MUT-4; FabI inhibitors (antibacterial), Mutabilis; FabI inhibitors (bacterial infection), FAB Pharma
Indication Methicillin-resistant staphylococcus aureus infection [ICD10:B95.62] Preclinical [548048]
Company
Mutabilis SA
Structure
Download
2D MOL

3D MOL
Canonical SMILES
c1c(c(cc(c1O)Oc1ccc(cc1F)C(=O)N)F)CC
Target and Pathway
Target(s) Staphylococcus aureus Enoyl ACP reductase Target Info Modulator [531594]
Escherichia coli NADH-dependent enoyl-ACP reductase Target Info Modulator [531594]
KEGG Pathway Fatty acid biosynthesis
Biotin metabolism
Metabolic pathways
Fatty acid metabolism
References
Ref 548048Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021501)
Ref 531594The MUT056399 inhibitor of FabI is a new antistaphylococcal compound. Antimicrob Agents Chemother. 2011 Oct;55(10):4692-7.

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