TTD | Drug: D0FH3X

Drug General Information
Drug ID	D0FH3X
Former ID	DNC006109
Drug Name	A-437203
Drug Type	Small molecular drug
Indication	Psychotic disorders [ICD9: 290-299; ICD10:F20-F29]		Discontinued in Phase 2	[547085]
Structure		Download 2D MOL 3D MOL
Formula	C20H27F3N6OS
Canonical SMILES	CC(C)(C)C1=NC(=CC(=N1)N2CCN(CC2)CCCSC3=NC=CC(=O)N3)C(F)<br />(F)F
InChI	1S/C20H27F3N6OS/c1-19(2,3)17-25-14(20(21,22)23)13-15(26-17)29-10-8-28(9-11-29)7-4-12-31-18-24-6-5-16(30)27-18/h5-6,13H,4,7-12H2,1-3H3,(H,24,27,30)
InChIKey	KXVAICSRMHXLJN-UHFFFAOYSA-N
PubChem Compound ID	9916104
Target and Pathway
Target(s)	D(3) dopamine receptor	Target Info	Modulator
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Dopaminergic synapse
Reactome	Dopamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	Nicotine Activity on Dopaminergic Neurons
	GPCRs, Other
References
Ref 547085	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012940)

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Drug Information