Drug General Information
Drug ID	D02MNR
Former ID	DIB007550
Drug Name	S-888711
Synonyms	Butyzamide; Thrombopoietin (TPO) mimetic (thrombocytopenia), Shionogi
Drug Type	Small molecular drug
Indication	Liver disease [ICD9: 570-574; ICD10:K70-K77]		Phase 2	[522925]
Company	Shionogi & Co Ltd
Structure		Download 2D MOL 3D MOL
Formula	C29H32Cl2N2O5S
Canonical SMILES	C(C)(C)(C(c1cccc(c2nc(sc2)NC(=O)c2cc(c(c(c2)Cl)/C=C(/C(<br />=O)O)\C)Cl)c1OC)OCCC)C
PubChem Compound ID	57887228
Target and Pathway
Target(s)	Thrombopoietin Receptor	Target Info	Agonist	[544267]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Jak-STAT signaling pathway
WikiPathways	Platelet Aggregation (Plug Formation)
References
Ref 522925	ClinicalTrials.gov (NCT01054443) A Study to Investigate the Efficacy and Safety of S-888711 Tablets Administered to Adult Subjects With Immune Thrombocytopenia (ITP). U.S. National Institutes of Health.
Ref 544267	Defective regulatory B-cell compartment in patients with immune thrombocytopenia. Blood. 2012 October 18; 120(16): 3318-3325.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.