Drug Information

Drug General Information
Drug ID
D0U5OU
Former ID
DIB011521
Drug Name
Naproxcinod
Synonyms
Beprana; Nitronaproxen; AR-P900758XX; AZD-3582; HCT-3012; Nitronaproxen, NicOx; NO-naproxen, AstraZeneca; NO-naproxen, NicOx; NO-NSAID, NicOx/AstraZeneca; Nitric oxide-donating derivative of naproxen (oral, osteoarthritis), NicOx
Drug Type
Small molecular drug
Indication Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] Phase 3 [522137]
Company
NicOx SA
Structure
Download
2D MOL

3D MOL
Formula
C18H21NO6
Canonical SMILES
[N+](=O)([O-])OCCCCOC(=O)[C@H](c1cc2c(cc(cc2)OC)cc1)C
CAS Number
CAS 163133-43-5
PubChem Compound ID
9884642
Target and Pathway
Target(s) Cyclooxygenase Target Info Modulator [537263]
References
Ref 522137ClinicalTrials.gov (NCT00541489) Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Hip. U.S. National Institutes of Health.
Ref 537263Naproxcinod, a new cyclooxygenase-inhibiting nitric oxide donator (CINOD). Expert Opin Biol Ther. 2009 May;9(5):649-57.

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