Drug General Information
Drug ID	D02OCD
Former ID	DIB009924
Drug Name	NIBR-785
Drug Type	Small molecular drug
Indication	Multiple scierosis [ICD9: 340; ICD10:G35]		Investigative	[543701]
Company	Novartis Institutes for BioMedical Research Inc
Structure		Download 2D MOL 3D MOL
Formula	C22H24N2O5
Canonical SMILES	CC(C)(c1ccc(NC(=O)c2c(=O)oc3c(c(ccc3c2)OC)OCC)cc1)N
PubChem Compound ID	46184240
Target and Pathway
Target(s)	Sphingosine 1-phosphate receptor 1	Target Info	Modulator	[543701]
KEGG Pathway	FoxO signaling pathway
	Sphingolipid signaling pathway
	Neuroactive ligand-receptor interaction
NetPath Pathway	IL4 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
	IL2 Signaling Pathway
Pathway Interaction Database	Fc-epsilon receptor I signaling in mast cells
	S1P3 pathway
	S1P1 pathway
	Sphingosine 1-phosphate (S1P) pathway
	PDGFR-beta signaling pathway
Reactome	G alpha (i) signalling events
	Lysosphingolipid and LPA receptors
WikiPathways	Signal Transduction of S1P Receptor
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 543701	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 275).
Ref 543701	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 275).

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