Drug General Information
Drug ID
D02VBL
Former ID
DIB013710
Drug Name
EMZ701
Synonyms
Interferon enhancing therapy
Indication HBV infection [ICD9: 070.2-070.3; ICD10:B16, B18.0, B18.1] Phase 2 [551742]
Company
Transition Therapeutics
Target and Pathway
Target(s) IFN-alphaR Target Info Modulator [550880]
KEGG Pathway Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Osteoclast differentiation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Hepatitis C
Hepatitis B
Measles
Influenza A
Herpes simplex infection
NetPath Pathway TCR Signaling Pathway
Leptin Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database Downstream signaling in na&#xef
Reactome Interferon alpha/beta signaling
Regulation of IFNA signaling
WikiPathways Toll-like receptor signaling pathway
Interferon type I signaling pathways
Interferon alpha/beta signaling
Regulation of toll-like receptor signaling pathway
Osteoclast Signaling
References
Ref 551742Clinical pipeline report, company report or official report of Transition Therapeutics.
Ref 550880Patent EP2766021 A1.

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