TTD | Drug: D0Y4PL

Drug General Information
Drug ID	D0Y4PL
Former ID	DIB014572
Drug Name	QAP-642
Synonyms	CCR3 antagonist (allergic rhinitis), Novartis
Indication	Allergic rhinitis [ICD9: 472.0, 477, 995.3; ICD10:J00, J30, J31.0, T78.4]		Terminated	[548218]
Company	Novartis AG
Target and Pathway
Target(s)	C-C chemokine receptor type 3	Target Info	Antagonist	[551842]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway
	Viral carcinogenesis
NetPath Pathway	IL3 Signaling Pathway
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Reactome	Chemokine receptors bind chemokines
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	IL1 and megakaryotyces in obesity
	IL-3 Signaling Pathway
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 548218	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023202)
Ref 551842	New Drugs and Targets for Asthma and COPD. T.T. Hansel, P.J. Barnes. 2010. Page 158.

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Drug Information