Drug General Information
Drug ID
D0G6PG
Former ID
DIB012936
Drug Name
CPA-926
Synonyms
6-(2-Acetamido-2-deoxy-beta-D-glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
Indication Arthritis [ICD9: 710-719; ICD10:M00-M25] Discontinued in Phase 2 [547639]
Structure
Download
2D MOL

3D MOL

Target and Pathway
Target(s) Lipoxygenase Target Info Modulator [525444]
References
Ref 547639Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018063)
Ref 525444Esculetin (dihydroxycoumarin) inhibits the production of matrix metalloproteinases in cartilage explants, and oral administration of its prodrug, CPA-926, suppresses cartilage destruction in rabbit experimental osteoarthritis. J Rheumatol. 1999 Mar;26(3):654-62.

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