Drug Information
Drug General Information | |||||
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Drug ID |
D00TXL
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Former ID |
DIB001147
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Drug Name |
AAV2-hFIX16
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Synonyms |
AAV-F.IX, University of Pennsylvania; AAV-factor IX gene therapy (hemophilia B), University of Pennsylvania
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Indication | Factor IX deficiency [ICD10:D67] | Phase 1 | [522086] | ||
Company |
University of Pennsylvania
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Target and Pathway | |||||
Target(s) | Coagulation factor IX | Target Info | Modulator | [544166] | |
KEGG Pathway | Complement and coagulation cascades | ||||
PANTHER Pathway | Blood coagulation | ||||
PathWhiz Pathway | Coagulation | ||||
Reactome | Extrinsic Pathway of Fibrin Clot Formation | ||||
Intrinsic Pathway of Fibrin Clot Formation | |||||
Gamma-carboxylation of protein precursors | |||||
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
References |
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