Drug Information

Drug General Information
Drug ID
D0ET2T
Former ID
DNCL003568
Drug Name
GSK2586881
Synonyms
GSK-2586881
Indication Acute lung injury [ICD9: 518; ICD10:J80] Phase 2 [523900]
Company
GlaxoSmithKline
Target and Pathway
Target(s) Recombinant human angiotensin converting enzyme 2 Target Info Modulator [544476]
KEGG Pathway Renin-angiotensin system
Protein digestion and absorption
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 523900ClinicalTrials.gov (NCT01597635) The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury. U.S. National Institutes of Health.
Ref 544476New Developments in the Pharmacological Treatment of Hypertension: Dead-End or a Glimmer at the Horizon?. Curr Hypertens Rep. 2015; 17(6): 42.

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