TTD | Drug: D08DTD

Drug General Information
Drug ID	D08DTD
Former ID	DIB009257
Drug Name	Biostrophin
Synonyms	Duchenne muscular dystrophy therapy, Asklepios; Adeno-associated virus gene therapy (dystrophin), AskBio; Adeno-associated virus gene therapy (dystrophin), Asklepios
Indication	Duchenne muscular dystrophy [ICD10:G71.0]		Phase 1	[548212]
Company	Asklepios biopharmaceuticals
Target and Pathway
Target(s)	Dystrophin	Target Info	Modulator	[525393]
KEGG Pathway	Hypertrophic cardiomyopathy (HCM)
	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
	Dilated cardiomyopathy
	Viral myocarditis
NetPath Pathway	IL4 Signaling Pathway
NetPath Pathway	IL5 Signaling Pathway
Reactome	Non-integrin membrane-ECM interactions
Reactome	Striated Muscle Contraction
WikiPathways	Striated Muscle Contraction
	Ectoderm Differentiation
	Extracellular matrix organization
	Arrhythmogenic Right Ventricular Cardiomyopathy
	Muscle contraction
References
Ref 548212	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023141)
Ref 525393	Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches. Nat Rev Genet. 2013 Jun;14(6):373-8. doi: 10.1038/nrg3460. Epub 2013 Apr 23.

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Drug Information