Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08JVS
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| Former ID |
DIB010604
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| Drug Name |
NU-206
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| Synonyms |
HRSpo-1; Secreted proteins (IBD), ARCA; Secreted proteins (mucositis), ARCA; Secreted proteins (GI and bone diseases),Kyowa Hakko Kirin/ARCA; Secreted proteins (IBD), Kirin/ARCA; Secreted proteins (inflammatory bowel disease), ARCA/Kirin; Secreted proteins (mucositis), Kirin/ARCA; Human R-Spondin-1 (GI and bone diseases), ARCA; Low-density lipoprotein receptor related protein 6 (IBD), Kirin/ARCA
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| Company |
Kirin Brewery Co Ltd
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| Target and Pathway | |||||
| Target(s) | Roof plate-specific spondin 1 | Target Info | Modulator | ||
| Pathway Interaction Database | Wnt signaling network | ||||
| Reactome | Regulation of FZD by ubiquitination | ||||
| References | |||||
| Ref 529021 | R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14700-5. Epub 2007 Sep 5. | ||||
| Ref 540504 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3697). | ||||
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