Drug Information
Drug General Information | |||||
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Drug ID |
D0A9PW
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Former ID |
DIB000502
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Drug Name |
AMT-060
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Synonyms |
AAV gene therapy (hemophilia B), Amsterdam Molecular Therapeutics/St Jude
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Indication | Factor IX deficiency [ICD10:D67] | Phase 1/2 | [548603] | ||
Company |
Amsterdam Molecular Therapeutics BV
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Target and Pathway | |||||
Target(s) | Coagulation factor IX | Target Info | Modulator | [550344] | |
KEGG Pathway | Complement and coagulation cascades | ||||
PANTHER Pathway | Blood coagulation | ||||
PathWhiz Pathway | Coagulation | ||||
Reactome | Extrinsic Pathway of Fibrin Clot Formation | ||||
Intrinsic Pathway of Fibrin Clot Formation | |||||
Gamma-carboxylation of protein precursors | |||||
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
References |
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