Drug Information

Drug General Information
Drug ID
D08VAR
Former ID
DIB015100
Drug Name
APH-0812
Synonyms
Bryostatin-1 + HDAC inhibitor combination (HIV-1 infection), Aphios
Indication HIV-1 infection [ICD9: 001-139, 042; ICD10:B20-B24] Phase 2 [526936], [528914]
Company
Aphios Corp
Target and Pathway
Target(s) Protein kinase C Target Info Inhibitor [526936], [528914]
Histone deacetylase Target Info Inhibitor [526936], [528914]
References
Ref 526936Bryostatin-1: a novel PKC inhibitor in clinical development. Cancer Invest. 2003;21(6):924-36.
Ref 528914Targeting the protein kinase C family: are we there yet. Nat Rev Cancer. 2007 Jul;7(7):554-62.
Ref 526936Bryostatin-1: a novel PKC inhibitor in clinical development. Cancer Invest. 2003;21(6):924-36.
Ref 528914Targeting the protein kinase C family: are we there yet. Nat Rev Cancer. 2007 Jul;7(7):554-62.

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