Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0K5QY
|
||||
| Former ID |
DIB000061
|
||||
| Drug Name |
AP-101
|
||||
| Indication | Ischemia [ICD9: 459.89; ICD10:I99.8] | Investigative | [1] | ||
| Company |
Aprogen Inc
|
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| Target and Pathway | |||||
| Target(s) | Angiopoietin 1 receptor | Target Info | Modulator | [1] | |
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| HIF-1 signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| Rheumatoid arthritis | |||||
| NetPath Pathway | Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| Pathway Interaction Database | Angiopoietin receptor Tie2-mediated signaling | ||||
| SHP2 signaling | |||||
| Reactome | Tie2 Signaling | ||||
| RAF/MAP kinase cascade | |||||
| WikiPathways | Wnt Signaling Pathway Netpath | ||||
| Cell surface interactions at the vascular wall | |||||
| Angiogenesis | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1842). | ||||
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